🧬AC-262 (AC-262536)
Overview
AC-262, also known as AC-262536, is a non-steroidal Selective Androgen Receptor Modulator (SARM) developed to provide anabolic benefits—such as muscle growth and strength—with minimal androgenic side effects. Still in the experimental phase, AC-262 is considered a milder, cleaner alternative to stronger SARMs like RAD-140 or LGD-4033. Its unique profile makes it a promising candidate for muscle preservation, body recomposition, and age-related muscle loss therapy with less hormonal suppression.
📂 Category
Hormonal Modulators
Selective Androgen Receptor Modulators (SARMs)
🔬 Molecular Profile
Chemical Name: (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide
Molecular Formula: C₁₈H₁₈F₃N₃O₃
Molecular Weight: ~381.4 g/mol
Class: Non-steroidal SARM
Half-Life: Estimated ~12–16 hours (not clinically confirmed)
Binding Affinity: Moderate binding affinity to androgen receptors in muscle and bone tissue
📌 What Is AC-262?
Name: AC-262 or AC-262536
Type: Investigational SARM
Function: Selectively binds androgen receptors to stimulate anabolic effects in muscle and bone
Use: Studied for muscle preservation, athletic performance, and HRT alternatives
Distinguishing Trait: Considered a "mild" SARM—lower suppression, fewer androgenic risks
🧪 Mechanism of Action
AC-262 works by selectively activating androgen receptors (ARs) in skeletal muscle and bone, while sparing organs like the prostate and liver:
Stimulates anabolic activity (protein synthesis, hypertrophy)
Minimizes androgenic effects like hair loss, prostate growth, and acne
Does not convert to estrogen (non-aromatizing)
May preserve hypothalamic-pituitary-gonadal (HPG) axis function better than more potent SARMs
🩺 Most Common Uses
⚕️ Potential Benefits
Anabolic Support
Increases muscle protein synthesis and lean mass
Helps preserve strength during cutting phases
May support bone density in age-related or osteopenic conditions
Hormonal & Androgenic Balance
Very low androgenic activity (less than 1% of testosterone)
Minimal impact on DHT or estrogen pathways
May result in less suppression of LH/FSH vs stronger SARMs
Health & Recovery
Enhances muscle regeneration and performance
May promote metabolic health without affecting cholesterol or liver enzymes
💉 Administration & Dosage
Delivery Forms
Oral capsules or liquid – standard format via research chemical suppliers
Typical Research Dosages
📚 Scientific Research
Animal Studies: Demonstrated significant anabolic effects in muscle with minimal androgenic stimulation of prostate tissue
Binding Affinity: Less potent than RAD-140 or LGD-4033, but with a cleaner hormonal footprint
Neuroprotection: Preliminary animal research suggests potential neuroprotective effects via AR stimulation in the brain
No large-scale human clinical trials are available yet—AC-262 remains a research-only compound.
⚠️ Safety & Side Effects
Common Side Effects
Mild testosterone suppression (dose-dependent)
Rare fatigue, insomnia, or irritability
No reported liver toxicity or estrogen-related issues
Estrogen-Related Side Effects
Non-aromatizing → No conversion to estrogen
No DHT conversion, lowering risk of acne, hair loss, or prostate growth
PCT Consideration
Check testosterone, LH/FSH, estradiol, and lipid panels pre- and post-cycle
PCT may or may not be necessary depending on dose and duration
📜 Legal & Regulatory Status
FDA Status: Not approved for medical use; under experimental development
Research Use: Legal to purchase for laboratory research purposes only
WADA Status: Prohibited in competitive sports
Supplement Use: Not legal for sale as a dietary supplement
❓ FAQ
Is AC-262 a steroid?
No – AC-262 is a non-steroidal SARM that selectively binds to androgen receptors in muscle and bone.
How does AC-262 compare to RAD-140 or LGD-4033?
It’s less potent but also less suppressive, making it suitable for milder cycles or for those concerned about side effects.
Does it require PCT?
Possibly not at lower doses, but bloodwork is critical. For cycles over 6 weeks, a light PCT is advised.
Is AC-262 safe for women?
It may be, at very low doses, but clinical data is lacking. Female use should be cautious and monitored.
🔍 Summary
AC-262 is a mild yet effective SARM that offers lean muscle support, fat metabolism, and hormonal balance without the harsher suppression seen with stronger SARMs. Its low androgenic profile and clean safety margin make it an ideal candidate for first-time users, bridging protocols, or individuals seeking safer anabolic effects without committing to full-blown TRT or steroid cycles.
Disclaimer: This content is for informational use only and does not constitute medical advice.
Sourcing
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